FIRST-LINE Synonyms: 24 Similar and Opposite Words

first-line

adjective

ˈfərst-ˈlīn

Definition of first-line

as in selected

singled out from a number or group as more to one's liking surgery is usually not considered a first-line treatment for this type of cancer

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Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.

Recent Examples of first-line Access antibiotics are first-line treatments for common infections and should be widely available. — Peter Beyer, STAT, 18 Aug. 2026 The first-line treatment is trimethoprim-sulfamethoxazole, sold under the brand names Bactrim, Septra, or Cotrim. — Tom Gavin, EverydayHealth.com, 11 Aug. 2026 The communication drills are intended to encourage first-line fighters to be more self-reliant and effective in battle, experts say. — ABC News, 5 Aug. 2026 Iron supplements are a first-line treatment to improve iron deficiency. — Ayesha Gulzar, Verywell Health, 31 July 2026 See All Example Sentences for first-line

Recent Examples of Synonyms for first-line

Adjective

Meanwhile, the first stage can handle different solid rocket motors for pre-selected range, speed, and performance profiles, as well as different booster types and other modular components.

— New Atlas, New Atlas, 17 Oct. 2026
The Pope Leo Village Homes initiative is underway in Bronzeville with five of the seven area homes under construction and two with selected homeowners.

— Everett Eaton, jsonline.com, 21 Aug. 2026

Definition of selected

Adjective

John Fogerty, rising singer-songwriter Emma Ogier, and others are slated to open on select dates.

— Angie Martoccio, Rolling Stone, 16 Oct. 2026
In practice, that means defaults can differ meaningfully between full-service and select-service properties within the same loyalty portfolio.

— Ashley Lynch, Kansas City Star, 16 Oct. 2026

Definition of select

Adjective

Our customers pair all of their favorite knits back to their favorite pair of jeans that’s vintage or what not.

— Lisa Lockwood, Footwear News, 14 Oct. 2026
Ahead, find our favorite chocolate brown suede pieces for fall, including boots, flats, and several fun ways to accessorize.

— Jessie Quinn, StyleCaster, 13 Oct. 2026

Definition of favorite

Adjective

An Ipsos poll out Friday finds that a majority, or about 51% of the population, say chocolate is their preferred Halloween candy of choice.

— ABC News, ABC News, 16 Oct. 2026
Poland never underestimated Russia threat watch now Choose CNBC as your preferred source on Google and never miss a moment from the most trusted name in business news.

— Lora Kolodny, CNBC, 16 Oct. 2026

Definition of preferred

Adjective

Not that the easily impressed senators, eager to exculpate a favored man, took note of the irony.

— Theater Critic, Los Angeles Times, 18 Sep. 2026
The Palazzo Dandolo Paolucci is one such overlooking the Grand Canal, a true rarity amidst the everyday, awaiting whomever its next favored owner might be.

— Nielsen Dinwoodie, Forbes.com, 20 Aug. 2026

Definition of favored

Browse Nearby Words

first lady

first-line

firstly

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“First-line.” Merriam-Webster.com Thesaurus, Merriam-Webster, https://www.merriam-webster.com/thesaurus/first-line. Accessed 20 Oct. 2026.

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Synonyms of first-line

adjective

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