How to Use clozapine in a Sentence
clozapine
noun-
When nothing else has worked, clozapine can, sometimes, give a person back to themselves.
—Nitin Gogtay, STAT, 4 Sep. 2026
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The goal was to catch the small number of patients in whom clozapine can sharply reduce the white cells that fight infection.
—Nitin Gogtay, STAT, 4 Sep. 2026
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And, in children with childhood-onset schizophrenia, clozapine.
—Nitin Gogtay, STAT, 4 Sep. 2026
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The cost of our avoidance of clozapine is invisible but enormous, measured in people who stay sick, and in lives that end early, for want of a drug already sitting on the shelf.
—Nitin Gogtay, STAT, 4 Sep. 2026
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Thus, the use of clozapine is associated with close medical monitoring for some patients, in the form of blood tests to measure the absolute neutrophil count.
—Encyclopedia Britannica, 7 Oct. 2026
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Another example is clozapine, a drug used to suppress delusions experienced by people with schizophrenia.
—C. Michael White, The Conversation, 13 Nov. 2025
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For example, since other drugs for schizophrenia do not carry the serious risks that clozapine does, clinicians usually reserve that medicine for people who could not use those other drugs.
—C. Michael White, The Conversation, 13 Nov. 2025
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With more widespread use, however, a rare, life-threatening side effect known as agranulocytosis (a severe reduction in white blood cells) emerged, prompting clozapine’s withdrawal from the market.
—Encyclopedia Britannica, 7 Oct. 2026
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Over time these requirements loosened, and in 2025 the FDA ended mandatory blood testing in conjunction with clozapine use.
—Encyclopedia Britannica, 7 Oct. 2026
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These observations shifted clozapine’s course of development from that of an antidepressant medication to investigation of its potential use as an antipsychotic drug.
—Encyclopedia Britannica, 7 Oct. 2026
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In 1961, however, studies in animals revealed that clozapine acts primarily as a sedative and exerts its effects without inducing muscle rigidity, as previous antipsychotics had.
—Encyclopedia Britannica, 7 Oct. 2026
Some of these examples are programmatically compiled from various online sources to illustrate current usage of the word 'clozapine.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.
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