: an estrogen antagonist C26H29NO used in the form of its citrate especially to treat postmenopausal breast cancer

Examples of tamoxifen in a Sentence

Recent Examples on the Web
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Peet, who had been screened since her late 30s because of dense breast tissue and prior benign lumps, was treated with a lumpectomy and radiation and is now on tamoxifen. — Samantha Agate, Kansas City Star, 14 Oct. 2026 Peet underwent a lumpectomy and radiation and now takes tamoxifen, a drug that blocks cancer cells from using estrogen and progesterone to grow. — Samantha Agate, Miami Herald, 14 Oct. 2026 After a moment’s thought, Greenwald told her to do the lumpectomy—and the tamoxifen, which would cut the chance of cancer recurrence in half. — Melanie Thernstrom, New Yorker, 29 June 2026 If the findings are confirmed, the risk score could help doctors tailor recommendations for surveillance intensity and risk-reduction strategies, including medications like tamoxifen or aromatase inhibitors, specifically for those high-risk women, says Roy. — Emily Kay Votruba, EverydayHealth.com, 2 Oct. 2025 See All Example Sentences for tamoxifen

Word History

Etymology

probably by recombination & alteration of trans-, oxy, and clomiphene

First Known Use

1972, in the meaning defined above

Time Traveler
The first known use of tamoxifen was in 1972

Browse Nearby Words

Cite this Entry

“Tamoxifen.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/tamoxifen. Accessed 20 Oct. 2026.

Medical Definition

tamoxifen

noun
: a selective estrogen receptor modulator that acts as an estrogen antagonist in breast tissue and is administered orally in the form of its citrate C26H29NO·C6H8O7 especially to treat breast cancer or reduce the risk of its development or reoccurrence see nolvadex

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