1
: of, relating to, or being a prosthesis
a prosthetic limb
prosthetic devices
These researchers will develop ways to connect prostheses more soundly to the bone, coordinate brain signals with prosthetic movement, and create properly rotating artificial joints.—Sheela Raman
Similar prevention is recommended if you have leaky, prolapsed, or prosthetic heart valves.—Consumer Reports
also : of or relating to prosthetics
prosthetic research
2
: of, relating to, or constituting a nonprotein group of a conjugated protein
covalently bound prosthetic groups
a heme prosthetic group

Examples of prosthetic in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
These days her Halloween costumes are often elaborate and prosthetic-heavy. — Marah Eakin, Los Angeles Times, 15 Oct. 2026 The Glass Onion star’s elaborate metamorphosis took six hours and a three-person glam team (makeup artist Sasha Glasser, prosthetic and special FX artist Chelsea Delfino, and FX makeup artist and body painter Malina Stearns) to achieve. — Christina Perrier, InStyle, 15 Oct. 2026 His face was made of 10 interlocking prosthetic pieces glued to his skin, which moved with his facial expressions. — Kenneal Patterson, Vanity Fair, 14 Oct. 2026 The docuseries needed a capable actress that, with 90 minutes of hair and makeup (and one prosthetic tooth), could kind of look like Wuornos. — Tony Maglio, HollywoodReporter, 30 Sep. 2026 See All Example Sentences for prosthetic

Word History

First Known Use

1872, in the meaning defined at sense 1

Time Traveler
The first known use of prosthetic was in 1872

Browse Nearby Words

Cite this Entry

“Prosthetic.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/prosthetic. Accessed 22 Oct. 2026.

Medical Definition

prosthetic

adjective
1
: of, relating to, or being a prosthesis
a prosthetic device
prosthetic limbs
also : of or relating to prosthetics
prosthetic research
2
: of, relating to, or constituting a nonprotein group of a conjugated protein
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