: a white crystalline nitrogenous substance C4H9N3O2 found especially in the muscles of vertebrates either free or as phosphocreatine
also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web
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When to See a Healthcare Provider B vitamins, magnesium, iron, vitamin D, CoQ10, creatine, and vitamin C all play different roles in the processes that keep your body functioning and producing energy. — Sara Hoffman, Verywell Health, 16 Oct. 2026 Perimenopausal women may also have lower brain creatine levels, potentially contributing to brain fog and memory lapses. — Maggie Ryan, Flow Space, 15 Oct. 2026 Adding creatine to an exercise and diet intervention resulted in greater reductions in body fat percentage, better preservation of lean body mass, and marked improvements in upper- and lower-body strength compared to a placebo. — Khloe Quill, FOXNews.com, 2 Oct. 2026 Thursdays and Fridays are after-work nights, and members can have a matcha, complete with collagen or creatine shots — or a beer or glass of wine. — Rhonda Richford, Footwear News, 28 Sep. 2026 See All Example Sentences for creatine

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Time Traveler
The first known use of creatine was in 1840

Browse Nearby Words

Cite this Entry

“Creatine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/creatine. Accessed 19 Oct. 2026.

Medical Definition

: a white crystalline nitrogenous substance C4H9N3O2 found especially in vertebrate muscle either free or as phosphocreatine

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