plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.—L. Stivitz
Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.—Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The radiant formula features a subtle sheen and amps skin’s moisture levels with ceramides and hyaluronic acid. — Conçetta Ciarlo, Vogue, 13 Oct. 2026 This moisturizer from Paula’s Choice contains five ceramides and cholesterol for an instant boost and plumpness, plus locks in moisture that will last throughout your red eye. — Liz Provencher, Travel + Leisure, 10 Oct. 2026 Tea tree leaf water and niacinamide prevent breakouts and tackle redness, while glycerin, panthenol, and ceramides keep skin hydrated and supported. — Christa Joanna Lee, Allure, 7 Oct. 2026 The peptide and ceramide complex also doubles down on hydration while plumping the skin and softening the appearance of fine lines around the eyes. — Olivia Cigliano, InStyle, 7 Oct. 2026 See All Example Sentences for ceramide

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of ceramide was in 1958

Browse Nearby Words

Cite this Entry

“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 20 Oct. 2026.

Medical Definition

: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
Elevated plasma levels of many of the sphingolipids have also been correlated with chronic disease—for example, sphingomyelins with coronary heart disease and ceramides with type 2 diabetes and Alzheimer's disease.—Oswald Quehenberger and Edward A. Dennis, The New England Journal of Medicine

More from Merriam-Webster on ceramide

Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!