: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

Examples of antibody in a Sentence

Recent Examples on the Web
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They are usually still protected by maternal antibodies, experts say. — Arkansas Online, 18 Oct. 2026 Not everyone who tests positive for alpha-gal antibodies develops a red meat allergy, Molaei said. — Stephen Underwood, Hartford Courant, 14 Oct. 2026 Syndax Pharmaceuticals — Shares tumbled 14% after the company said axatilimab did not meet its primary endpoint during a Phase 2 trial in which the antibody was used to treat idiopathic pulmonary fibrosis. — Fred Imbert, CNBC, 13 Oct. 2026 If needed, check with your pediatrician’s office about availability of the RSV antibody for your infant. — Adejare Atanda, Baltimore Sun, 13 Oct. 2026 See All Example Sentences for antibody

Word History

Etymology

anti- + body entry 1, after German Antikörper

First Known Use

1894, in the meaning defined above

Time Traveler
The first known use of antibody was in 1894

Browse Nearby Words

Cite this Entry

“Antibody.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/antibody. Accessed 20 Oct. 2026.

Kids Definition

: a substance produced by special cells of the body that combines with an antigen and counteracts its effects or those of the microscopic plant or animal on which the antigen may occur

Medical Definition

plural antibodies
: any of a large number of proteins of high molecular weight that are produced normally by specialized B cells after stimulation by an antigen and act specifically against the antigen in an immune response, that are produced abnormally by some cancer cells, and that typically consist of four subunits including two heavy chains and two light chains

called also immunoglobulin

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