1
: either of two retroviruses (Lentivirus humimdef1 and L. humimdef2) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

… the longer people are infected with HIV and the more immune-deficient they become, the more readily they seem to pass HIV to others.—Robert R. Redfield et al.
Years of careful research have proven beyond doubt that the HIV virus causes AIDS, that antiretroviral drug treatment saves lives, and that the drug nevirapine is safe and effective in preventing the spread of HIV from mothers to their babies.—Richard Marlink et al.

called also AIDS virus, human immunodeficiency virus

see also hiv-1, hiv-2
2
: the infection or disease caused by HIV
Early symptoms of HIV develop in 50 to 90 percent of people who are infected, usually beginning two to four weeks after exposure. … Because the signs and symptoms of … HIV may be similar to other common illnesses, such as mononucleosis, most people do not initially realize that they have HIV.—Paul E. Sax

Examples of HIV in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The nonprofit foundation helps fund biomedical research that aims to reduce the spread of HIV/AIDs on a global scale. — Erin Wisti, Footwear News, 17 Oct. 2026 As a part of her work, Jacqueline Seitz, deputy director of health privacy at the Legal Action Center, frequently speaks with patients who use drugs, are in recovery, are living with HIV, or are in treatment for substance use disorders. — Alex Rosenblat — Calmatters, STAT, 15 Oct. 2026 Magic Johnson is relentlessly positive, a quality that has served him well as a player, a businessman and even while living with HIV since 1991. — Steve Henson, Los Angeles Times, 12 Oct. 2026 To achieve that goal, the federal government focused its efforts on Tarrant, Dallas, and 46 other counties nationwide where the majority of new HIV cases are diagnosed each year. — Ciara McCarthy 9, Fort Worth Star-Telegram, 9 Oct. 2026 See All Example Sentences for HIV

Word History

First Known Use

1986, in the meaning defined at sense 1

Time Traveler
The first known use of HIV was in 1986

Browse Nearby Words

Cite this Entry

“HIV.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/HIV. Accessed 19 Oct. 2026.

Kids Definition

: any of a group of viruses that infect and destroy helper T cells causing the marked reduction in their numbers that is diagnostic of AIDS

Medical Definition

1
: either of two retroviruses (Lentivirus humimdef1 and L. humimdef2) that infect and destroy helper T cells of the immune system and that when left untreated cause AIDS

Note: HIV retroviruses are transmitted through contact with blood, semen, rectal and vaginal fluids, or breast milk and typically cause flu-like symptoms during the acute phase of infection, but often cause few or no symptoms during the chronic phase of infection when treated with antiretroviral drugs.

called also AIDS virus, human immunodeficiency virus

see also hiv-1, hiv-2
2
: the infection or disease caused by HIV
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